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Akihisa Takahashi Selected Research

2-(morpholin-4-yl)benzo(h)chromen-4-one

5/2017Homologous recombination preferentially repairs heat-induced DNA double-strand breaks in mammalian cells.
11/2015Combining carbon ion irradiation and non-homologous end-joining repair inhibitor NU7026 efficiently kills cancer cells.

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Akihisa Takahashi Research Topics

Disease

44Neoplasms (Cancer)
01/2022 - 04/2002
6Glioblastoma (Glioblastoma Multiforme)
09/2015 - 04/2002
5Chromosome Aberrations (Chromosome Abnormalities)
09/2020 - 06/2008
4Neoplasm Metastasis (Metastasis)
01/2022 - 12/2018
4Osteosarcoma (Osteogenic Sarcoma)
05/2020 - 11/2019
4Lung Neoplasms (Lung Cancer)
12/2015 - 07/2006
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2008 - 03/2002
3Hyperthermia
06/2019 - 01/2003
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2015 - 03/2015
3Anaplastic Thyroid Carcinoma
01/2011 - 10/2002
2Hypoxia (Hypoxemia)
01/2022 - 10/2004
2Squamous Cell Carcinoma of Head and Neck
04/2012 - 07/2005
2Fanconi Anemia (Fanconi's Anemia)
05/2011 - 01/2011
2Nijmegen Breakage Syndrome
01/2011 - 01/2010
2Necrosis
10/2004 - 09/2002
2Carcinoma (Carcinomatosis)
04/2004 - 07/2002
1Radiation Injuries (Radiation Sickness)
01/2023
1Bone Resorption
11/2019
1Genomic Instability
09/2019
1Atrophy
12/2018
1Melanoma (Melanoma, Malignant)
11/2017
1Brain Neoplasms (Brain Tumor)
09/2015
1Adenocarcinoma of Lung
07/2014
1Mouth Neoplasms (Oral Cancer)
05/2014
1Hepatocellular Carcinoma (Hepatoma)
04/2013
1Complementation Group D1 Fanconi Anemia
05/2011
1Glioma (Gliomas)
08/2010
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2010

Drug/Important Bio-Agent (IBA)

11CarbonIBA
01/2022 - 07/2002
8Bromodeoxyuridine (BrdU)IBA
06/2019 - 12/2002
6DNA (Deoxyribonucleic Acid)IBA
05/2017 - 01/2010
6Proteins (Proteins, Gene)FDA Link
04/2012 - 03/2002
5SuspensionsIBA
12/2018 - 12/2002
5Small Interfering RNA (siRNA)IBA
01/2011 - 09/2006
4Radiation-Sensitizing AgentsIBA
11/2015 - 07/2008
4Cytochalasin BIBA
08/2005 - 01/2003
4Glycerol (Glycerine)FDA LinkGeneric
07/2005 - 04/2002
3Zoledronic Acid (Zometa)FDA Link
05/2020 - 11/2019
3WortmanninIBA
06/2019 - 05/2003
3Caspase 9IBA
07/2012 - 02/2004
3Caspase 3 (Caspase-3)IBA
07/2012 - 04/2004
3Temozolomide (Temodar)FDA LinkGeneric
05/2011 - 10/2009
2IonsIBA
01/2022 - 09/2019
2Fluorouracil (Carac)FDA LinkGeneric
11/2020 - 05/2014
2Antineoplastic Agents (Antineoplastics)IBA
11/2020 - 05/2014
22-(morpholin-4-yl)benzo(h)chromen-4-oneIBA
05/2017 - 11/2015
2DNA-Activated Protein KinaseIBA
11/2015 - 01/2010
2Paclitaxel (Taxol)FDA LinkGeneric
03/2015 - 01/2003
2NimustineIBA
05/2011 - 08/2010
2Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2011 - 06/2010
2bisbenzimide ethoxide trihydrochloride (Hoechst 33342)IBA
11/2010 - 06/2010
2Cisplatin (Platino)FDA LinkGeneric
01/2010 - 01/2003
2Indicators and Reagents (Reagents)IBA
12/2008 - 02/2004
2Ethidium (Ethidium Bromide)IBA
10/2004 - 09/2002
2Acridine OrangeIBA
10/2004 - 09/2002
1MelatoninIBA
01/2023
1Retinal Pigments (Pigments, Visual)IBA
01/2022
1hydroxide ionIBA
05/2020
1AllergensIBA
01/2020
1mouse MIRN29 microRNAIBA
01/2020
1Diphosphonates (Bisphosphonates)IBA
11/2019
1mahuang-tangIBA
06/2019
1Caffeine (No Doz)FDA LinkGeneric
06/2019
1MicroRNAs (MicroRNA)IBA
11/2017
1Protons (Proton)IBA
01/2016
1adavosertibIBA
12/2015
1Carboplatin (JM8)FDA LinkGeneric
03/2015
1Y 27632IBA
07/2014
1Transfer RNA (tRNA)IBA
04/2013
1CamptothecinIBA
04/2012
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
04/2012
1Topoisomerase I InhibitorsIBA
04/2012
1Poly(ADP-ribose) Polymerase InhibitorsIBA
04/2012
1olaparibIBA
04/2012
1Alkylating AgentsIBA
05/2011
1Formaldehyde (Formol)FDA Link
01/2011
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
01/2011
1Coloring Agents (Dyes)IBA
11/2010
1Sirolimus (Rapamycin)FDA Link
10/2010
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
10/2010
1deoxyuridine triphosphateIBA
06/2010
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
06/2010
1Serine (L-Serine)FDA Link
01/2010
1Checkpoint Kinase 2IBA
01/2010
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
01/2010
1Methenamine (Hexamine)IBA
01/2010
1Threonine (L-Threonine)FDA Link
01/2010
1Histones (Histone)IBA
01/2010
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
06/2008
1Peptides (Polypeptides)IBA
06/2008
1nutlin 3IBA
06/2008
12- phenyl- 4,4,5,5- tetramethylimidazoline- 1- oxyl- 3- oxideIBA
06/2008

Therapy/Procedure

15Therapeutics
11/2019 - 07/2002
10Radiotherapy
12/2021 - 07/2002
7Drug Therapy (Chemotherapy)
05/2014 - 10/2002
5Heavy Ion Radiotherapy
01/2022 - 01/2010
2Induced Hyperthermia (Thermotherapy)
11/2019 - 07/2008
1Immunotherapy
01/2022
1Intravenous Administration
11/2019
1Aftercare (After-Treatment)
01/2011